Deploy Sinefa Probe
You must have a Sinefa Probe deployed inside the network to get Application Visibility.
Layer 7 Visibility - Deep Packet Inspection (DPI)
This is the deepest form of application visibility available to Sinefa. The actual traffic itself needs to be inspected by a Sinefa Probe which subsequently classifies and monitors the traffic. If there is a way for a Sinefa Probe to see the traffic whether its by SPAN, TAP or inline and you want the best possible visibility then this is the method of choice. See here on how to Configure Sinefa for Layer 7.
Sinefa Best Practise Guide